Nanocarriers for brain targeting : principles and applications

Description

“This new volume, Nanocarriers for Brain Targeting: Principles and Applications, covers recent research on brain physiology and the development of drug delivery systems. It explores a diverse variety of strategies that can be employed to achieve drug targeting to the brain. The nanocarriers that are discussed include nanoparticles, vesicular carriers, carriers having carbon as a core constituent, dispersed systems, and more. The inherent anatomy and physiology of the brain renders it different from other organs. The past few decades have witnessed significant research on brain ailments in response to a majority of hospitalizations that occur due to age-related central nervous system disorders. The prevalence of diverse diseases such as Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, multiple sclerosis, HIV-dementia, etc., affect about 1.5 billion people globally, which is further anticipated to reach 1.9 billion by the year 2020. Nanocarriers for drug delivery to the brain are seen as one of the answers to this growing problem. The blood brain barrier (BBB) blocks the passage of certain substances, posing a challenge to effective drug delivery. The volume looks at how to circumvent this dilemma by designing and developing drug delivery carriers that are be able to deliver drugs across the BBB in a safe and effective fashion. Topics include: carriers for brain targeting challenges of the blood-brain barrier nanotechnology for brain targeting nanocapsules in brain targeting quantum dots for brain targeting liposomes for brain delivery nanogels and nanoemulsions for brain targeting This volume, with contributions from experience researchers in the field, helps to meet the high demand for new information on novel nanocarriers products for brain targeting around the world.”– Provided by publisher